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Clinical inquiries. What's the best drug treatment for premature ejaculation?
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Cyclic nucleotide phosphodiesterases (PDEs) are enzymes that regulate the cellular levels of the second messengers, cAMP and cGMP, by controlling their rates of degradation. There are 11 different PDE families, with each family typically having several different isoforms and splice variants. These unique PDEs differ in their three-dimensional structure, kinetic properties, modes of regulation, ...
متن کاملPhosphodiesterase type 5 inhibitor use and hearing impairment.
OBJECTIVE To compare use of phosphodiesterase type 5 inhibitors (PDE-5i) between participants with and without self-reported hearing impairment using logistic regression, with and without adjustment for potentially confounding sociodemographic, behavioral, and health-related characteristics. DESIGN Cross-sectional. SETTING United States. PATIENTS A population-based sample of 11 525 men 40...
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عنوان ژورنال:
- South Dakota journal of medicine
دوره 58 4 شماره
صفحات -
تاریخ انتشار 2005